PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule ▼ | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
C-terminal domain of toxin A molecules
|
unnamed ligand
|
Oligosaccharides
|
Human colonic cells
|
GalNAc(b1-3)Gal(b1-4)GlcNAc
|
Binding
|
||
Botulinum neurotoxin (type D)
|
Phosphatidylethanolamine (PE)
|
Non-glycosylated Lipids
|
Presynaptic neuronal cells
|
Binding
|
|||
Botulinum neurotoxin (type C)
|
GD1b
|
Disialoglycosphingolipids
|
Presynaptic neuronal cells
|
Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Botulinum neurotoxin (type C)
|
GT1b
|
Trisialoglycosphingolipids
|
Presynaptic neuronal cells
|
NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Botulinum neurotoxin (16S)
|
Lactose
|
Disaccharides
|
Intestinal epithelial cells (T84)
|
Gal(b1-4)Glc
|
Binding
|
||
Botulinum neurotoxin (16S)
|
N-Acetylgalactosamine
|
Monosaccharides
|
Intestinal epithelial cells (T84)
|
GalNAc
|
Binding
|
||
Botulinum neurotoxin (16S)
|
Galactose
|
Monosaccharides
|
Intestinal epithelial cells (T84)
|
Gal
|
Binding
|
||
Botulinum neurotoxin (16S)
|
N-Acetylglucosamine
|
Monosaccharides
|
Intestinal epithelial cells (T84)
|
GlcNAc
|
Not Binding
|
||
Botulinum neurotoxin (16S)
|
Mannose
|
Monosaccharides
|
Intestinal epithelial cells (T84)
|
Man
|
Not Binding
|
||
Botulinum neurotoxin (16S)
|
Glucose
|
Monosaccharides
|
Intestinal epithelial cells (T84)
|
Glc
|
Not Binding
|
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01