GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▲	Target Source	Glycan Sequence	Binding	PubMed ID
Escherichia coli	hLT	Blood group A antigen analog	Oligosaccharides			Binding	18809496
Actinomyces naeslundii	Unknown	unnamed ligand	Polyglycosylceramides	Rat small intestine	GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	2358461
Actinomyces viscosus	Unknown	unnamed ligand	Polyglycosylceramides	Rat small intestine	GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461
Shigella dysenteriae	B subunit	unnamed ligand	Polyglycosylceramides	Rat small intestine	GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5	Not Binding	3543013
Shigella dysenteriae	Shiga toxin	unnamed ligand	Polyglycosylceramides		GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5	Not Binding	2435422
Escherichia coli	Unknown	unnamed ligand	Polyglycosylceramides		GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5	Binding	2435422
Shigella dysenteriae	Unknown	unnamed ligand	Polyglycosylceramides		GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5	Not Binding	2435422
Neisseria meningitidis	OpcA	Sialic acid-containing polysaccharides	Polysaccharides	Epithelial cells		Binding	18076035
Bordetella pertussis	FHA (442-863)	Dextran sulfate	Polysaccharides	WiDr cells, HeLa cells, Vero cells, Extracellular matrix (ECM)		Binding	11348687
Human immunodeficiency virus	Unknown	Pentosan polysulfate (PP)	Polysaccharides	Human T cells		Binding	9420059