GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Binding	PubMed ID
Borrelia burgdorferi	Unknown	Heparan sulfate (fraction: HS-D)	Glycosaminoglycans	Vero cells	Not Binding	9826395
Borrelia burgdorferi	Unknown	Heparan sulfate (fraction: HS-D)	Glycosaminoglycans	Vero cells	Not Binding	9826395
Foot-and-mouth disease virus	VP1 (RGD peptide)	Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface)	Glycosaminoglycans	Extracellular matrix (ECM)	Binding	9557639
Foot-and-mouth disease virus	VP1 (RGD peptide)	Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface)	Glycosaminoglycans	Extracellular matrix (ECM)	Binding	9557639
Foot-and-mouth disease virus	VP1 (RGD peptide)	Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface)	Glycosaminoglycans	Extracellular matrix (ECM)	Binding	9557639
Foot-and-mouth disease virus	VP1 (RGD peptide)	Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface)	Glycosaminoglycans	Extracellular matrix (ECM)	Binding	9557639
Foot-and-mouth disease virus	Natural ligand of integrin [alpha]v[beta]3	Chondroitin sulfate A	Glycosaminoglycans	Extracellular matrix (ECM)	Not Binding	8764038
Foot-and-mouth disease virus	Natural ligand of integrin [alpha]v[beta]3	Chondroitin sulfate C	Glycosaminoglycans	Extracellular matrix (ECM)	Not Binding	8764038
Streptococcus pneumoniae	CBPs (choline-binding proteins)	Sialic acid	Monosaccharides	Cytokine-activated cells	Binding	12640357
Helicobacter pylori	SabA (sialic acid-binding adhesin)	Sialic acid	Monosaccharides	Human neutrophils	Binding	15689619