GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule ▼	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Helicobacter pylori	BabA (blood group antigen binding adhesin)	Blood group H1 antigen (HSA)	Glycoproteins		Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD	Binding	15273394
Helicobacter pylori	BabA (blood group antigen binding adhesin)	Blood group B-Lewis b (BLeb) antigen	Oligosaccharides		Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc	Binding	15273394
Helicobacter pylori	BabA (blood group antigen binding adhesin)	Blood group A-Lewis b (ALeb) antigen	Oligosaccharides		GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc	Binding	15273394
Helicobacter pylori	BabA (blood group antigen binding adhesin)	Blood group A antigen	Oligosaccharides		GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc	Binding	15273394
Borrelia burgdorferi	BBK32	Dermatan sulfate	Glycosaminoglycans	Mammalian cell surface		Binding	16368999
Borrelia burgdorferi	BBK32	Heparin	Glycosaminoglycans	Mammalian cell surface		Binding	16368999
Borrelia burgdorferi	BBK32	GAGs (glycosaminoglycans)	Glycosaminoglycans			Binding	18833295
Borrelia burgdorferi	BBK32	Fibronectin	Glycoproteins			Binding	18833295
Shigella dysenteriae	B subunit	Gb4 (Globoside; Globotetraose; P antigen)	Oligoglycosylceramides	Human erythrocytes	GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	3543013
Shigella dysenteriae	B subunit	Gb2 (Galabiosylceramide)	Diosylceramides	Human meconium	Gal(a1-4)Gal(b1-1)Cer	Binding	3543013