PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▼ | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
VP8
|
Sialic acid
|
Monosaccharides
|
Epithelial cells of small intestine
|
Binding
|
|||
PT (subunit S3 of B oligomer)
|
Gangliosides
|
Sialoglycosphingolipids
|
Human alveolar macrophages
|
Binding
|
|||
Adhesins
|
Gangliosides
|
Sialoglycosphingolipids
|
Human leukocytes, Human neutrophils
|
Binding
|
|||
Pertussis toxin
|
Gangliosides
|
Sialoglycosphingolipids
|
Human alveolar macrophages
|
Binding
|
|||
Unknown
|
Gangliosides
|
Sialoglycosphingolipids
|
Bovine brain
|
Binding
|
|||
Botulinum neurotoxin
|
GT1b (complex with synaptotagmin II)
|
Trisialoglycosphingolipids
|
Presynaptic membrane of neuromuscular junction
|
Binding
|
|||
BoNT/B
|
GT1b (complex with synaptotagmin II)
|
Trisialoglycosphingolipids
|
Presynaptic membrane of neuromuscular junction
|
Binding
|
|||
Lectin-hemagglutinin adhesins
|
Acid glycosphingolipids
|
Acidic Glycosphingolipids
|
human granulocytes
|
Not Binding
|
|||
Lectin-hemagglutinin adhesins
|
Acid glycosphingolipids
|
Acidic Glycosphingolipids
|
human granulocytes
|
Not Binding
|
|||
Lectin-hemagglutinin adhesins
|
Acid glycosphingolipids
|
Acidic Glycosphingolipids
|
human granulocytes
|
Not Binding
|
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Partly supported by NIH Common Fund Grant #1U01GM125267-01