PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule ▼ | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
B subunit
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Human erythrocytes, Rat small intestine
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
B subunit
|
SSEA-3 (GSL) (Galactosyl globoside; Gb5)
|
Oligoglycosylceramides
|
Human kidney
|
Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
B subunit
|
unnamed ligand
|
Oligoglycosylceramides
|
Rat small intestine
|
[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=2-5
|
Not Binding
|
||
AgfA (curli)
|
Plasminogen
|
Glycoproteins
|
Binding
|
||||
AgfA (curli)
|
Fibronectin
|
Glycoproteins
|
Binding
|
||||
AgfA (curli)
|
Human contact phase proteins
|
Glycoproteins
|
Binding
|
||||
Ag I/II (Antigen I/II Family)
|
Salivary glycoprotein
|
Glycoproteins
|
Tooth surface
|
Binding
|
|||
Adhesins
|
Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside)
|
Monosialoglycosphingolipids
|
Human leukocytes, Human neutrophils
|
NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Adhesins
|
GM3(NeuAc)
|
Monosialoglycosphingolipids
|
Human gastric mucosa
|
NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Adhesins
|
terminal Gal(3SO4) β1- residues
|
Sulfoglycosphingolipids
|
Human lung, Human trachea
|
Gal(3SO4)(b
|
Binding
|
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01