GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Binding	PubMed ID
Helicobacter canis	Lectin-hemagglutinin adhesins	Acid glycosphingolipids	Acidic Glycosphingolipids	human granulocytes	Not Binding	12704182
Influenza virus	SNA lectins	Minor NeuAcα6-containing molecules	Glycoconjugates	Human leukocytes	Binding	11030743
Escherichia coli	Type 1-fimbriae	Glycoside p-nitrophenyl alpha-D-mannopyranoside	Glycoconjugates	Patient with urinary tract infection	Binding	6138149
Entamoeba histolytica	Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa).	β-2 and β-7 integrins	Glycoproteins	Intestinal cells	Binding	15322032
Sporothrix schenckii	Yeast cells and conidia	Fibronectin	Glycoproteins	Extracellular matrix (ECM)	Binding	11598061
Paracoccidioides brasiliensis	Adhesins	Fibronectin	Glycoproteins	Human type II alveolar cells (A549)	Binding	18083324
Streptococcus pyogenes	Protein F (Antigen I/II)	Fibronectin	Glycoproteins	Respiratory endothelial cells	Binding	10341176
Streptococcus pyogenes	Protein F (Antigen I/II)	Fibronectin	Glycoproteins	Respiratory epithelial cells	Binding	1385871
Adenovirus	Fibre proteins	HSA glycoconjugates	Glycoproteins	Human corneal epithelial(HEC) cells	Binding	15678425
Leptospira interrogans	Lsa24	Laminin	Glycoproteins	Extracellular matrix (ECM)	Binding	16954400