GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule ▼	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Shigella dysenteriae	B subunit	Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)	Oligoglycosylceramides	Human erythrocytes, Rat small intestine	Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	3543013
Shigella dysenteriae	B subunit	SSEA-3 (GSL) (Galactosyl globoside; Gb5)	Oligoglycosylceramides	Human kidney	Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	3543013
Shigella dysenteriae	B subunit	unnamed ligand	Oligoglycosylceramides	Rat small intestine	[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=2-5	Not Binding	3543013
Salmonella enteritidis	AgfA (curli)	Plasminogen	Glycoproteins			Binding	9973330
Salmonella enteritidis	AgfA (curli)	Fibronectin	Glycoproteins			Binding	9973330
Salmonella enteritidis	AgfA (curli)	Human contact phase proteins	Glycoproteins			Binding	9973330
Streptococcus mutans	Ag I/II (Antigen I/II Family)	Salivary glycoprotein	Glycoproteins	Tooth surface		Binding	10341176
Helicobacter pylori	Adhesins	Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside)	Monosialoglycosphingolipids	Human leukocytes, Human neutrophils	NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	10569742
Helicobacter pylori	Adhesins	GM3(NeuAc)	Monosialoglycosphingolipids	Human gastric mucosa	NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer	Binding	2037054
Bordetella pertussis	Adhesins	terminal Gal(3SO4) β1- residues	Sulfoglycosphingolipids	Human lung, Human trachea	Gal(3SO4)(b	Binding	1918002