GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▲	Target Source	Glycan Sequence	Binding	PubMed ID
Escherichia coli	A and B polypeptide subunits	GD1a	Disialoglycosphingolipids		NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	3290106
Escherichia coli	A and B polypeptide subunits	GD1b	Disialoglycosphingolipids		Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	3290106
Sendai virus	Unknown	GD1a	Disialoglycosphingolipids		NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	12628483
Influenza virus	Hemagglutinin (HA)	GD1a	Disialoglycosphingolipids		NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	12628483
Clostridium tetani	Unknown	GD1b	Disialoglycosphingolipids		Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	9038159
Clostridium tetani	Unknown	GD1b	Disialoglycosphingolipids		Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	7527546
Clostridium botulinum	Unknown	GD1a	Disialoglycosphingolipids		NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	9712688
Legionella pneumophila	Adhesins	GD1a	Disialoglycosphingolipids	Human epithelial cells (respiratory tract)	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	14687561
Actinomyces viscosus	Unknown	GD1a	Disialoglycosphingolipids	Human brain	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461
Actinomyces viscosus	Unknown	GD1b	Disialoglycosphingolipids	Human brain	Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461