GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence ▲	Binding	PubMed ID
Lactobacillus johnsonii	Unknown	B6 type 2 glycosphingolipid (B6-2)	Oligoglycosylceramides	Human erythrocytes	Gal(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	11087711
Shigella dysenteriae	B subunit	B6 type 2 glycosphingolipid (B6-2)	Oligoglycosylceramides	Human erythrocytes	Gal(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	3543013
Actinomyces viscosus	Unknown	unnamed ligand	Oligoglycosylceramides	Various sources	Gal(a1-3)[Fuc(a1-2)]Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461
Actinomyces naeslundii	Unknown	unnamed ligand	Oligoglycosylceramides	Various sources	Gal(a1-3)[Fuc(a1-2)]Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461
Escherichia coli	PapG	alpha-D-galactopyranosyl-(1-4)-beta-D-galactopyranose	Disaccharides	Uroepithelial cells	Gal(a1-4)Gal	Binding	2886993
Escherichia coli	P-fimbriae	Gal alpha 1-4 Gal-containing glicolipids	Glycolipids	Pyelonephritis patients	Gal(a1-4)Gal	Binding	8574698
Escherichia coli	PapG	Gal alpha 1-4 Gal-containing glicolipids	Glycolipids	Pyelonephritis patients	Gal(a1-4)Gal	Binding	8574698
Escherichia coli	Verotoxin (1; B-subunit)	CD77 (Globotriaosylceramide; Gb3)	Oligoglycosylceramides	Germinal center B lymphocytes, Burkitt's lymphoma cells	Gal(a1-4)Gal	Binding	7516406
Escherichia coli	Unknown	CD77 (Globotriaosylceramide; Gb3)	Oligoglycosylceramides	Germinal center B lymphocytes, Burkitt's lymphoma cells	Gal(a1-4)Gal	Binding	7516406
Streptococcus suis	PO	unnamed ligand	Oligosaccharides	human erythrocytes	Gal(a1-4)Gal	Binding	7499414