GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Binding	PubMed ID
Entamoeba histolytica	Raft-like plasma membrane domains	β-2 and β-7 integrins	Glycoproteins	Intestinal cells	Binding	15322032
Foot-and-mouth disease virus	VP1 (RGD peptide)	Heparin	Glycosaminoglycans	Extracellular matrix (ECM)	Not Binding	9557639
Foot-and-mouth disease virus	Natural ligand of integrin [alpha]v[beta]3	De-N-sulfated heparin	Glycosaminoglycans	Extracellular matrix (ECM)	Not Binding	8764038
Human immunodeficiency virus	Unknown	NAC-heparin (non-anticoagulant heparin)	Glycosaminoglycans	Human T cells	Binding	9420059
Chlamydia trachomatis	Unknown	NAC-heparin (non-anticoagulant heparin)	Glycosaminoglycans	HeLa cells	Binding	9420059
Herpes simplex virus	Unknown	NAC-heparin (non-anticoagulant heparin)	Glycosaminoglycans	Human cervical cells	Binding	9420059
Neisseria gonorrhoeae	Unknown	NAC-heparin (non-anticoagulant heparin)	Glycosaminoglycans	Human epithelial cells	Binding	9420059
Helicobacter pylori	Adhesins	PGCs (polyglycosyl ceramides)	Glycosphingolipids	Human leukocytes, Human neutrophils	Binding	10569742
Helicobacter pylori	Unknown	PGCs (polyglycosyl ceramides)	Glycosphingolipids	Human erythrocytes, Human leukocytes, Human placenta	Binding	9169796
Helicobacter pylori	Unknown	PGCs (polyglycosyl ceramides)	Glycosphingolipids	Rat small intestine, Wild boar intestine, Monkey intestine	Binding	9169796