GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▲	Target Source	Glycan Sequence	Binding	PubMed ID
Haemophilus influenzae	Hia	unknown carbohydrate ligand	Saccharides	Human conjunctival cells (respiratory tract)		Binding	10341176
Actinomyces odontolyticus	Unknown	unknown carbohydrate ligand	Saccharides	Tongue		Binding	9712794
Streptococcus pneumoniae	PclA (pneumococcal collagen-like protein A)	unknown carbohydrate ligand	Saccharides	Detroit 562/A549 cell lines		Binding	18557785
Bordetella pertussis	Pertactin	unknown carbohydrate ligand	Saccharides	Eukaryotic cells		Binding	11348687
Anaplasma marginale	"MSP1a, MSP1b, MSP2"	unknown carbohydrate ligand	Saccharides			Binding	16299269
Influenza virus	Unknown	NeuAc3-Lc4Cer (Sialyl lactotetraosylceramide)	Sialoglycosphingolipids		NeuAc(a2-3)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	7870741
Actinomyces viscosus	Unknown	unnamed ligand	Sialoglycosphingolipids	Frog brain	NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461
Mycoplasma pneumoniae	Unknown	I-active Sialyl lactoisooctaosylceramide	Sialoglycosphingolipids	Human colon adenocarcinoma cells (WiDr )	Gal(a1-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2470753
Lactobacillus johnsonii	Unknown	unnamed ligand	Sialoglycosphingolipids	Bovine buttermilk	Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	11087711
Lactobacillus johnsonii	Unknown	NeuGc3-nLc6Cer	Sialoglycosphingolipids	Rabbit thymus	NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	11087711