PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species ▼ | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
FHA (1141-1279)
|
Lactosylceramide (Lactocerebroside)
|
Diosylceramides
|
Ciliated epithelium of the respiratory tract
|
Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
PT (subunit S2 of B oligomer)
|
Lactosylceramide (Lactocerebroside)
|
Diosylceramides
|
Human cilia of the respiratory epithelium
|
Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Adhesins
|
Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)
|
Oligoglycosylceramides
|
Human lung, Human trachea
|
Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
FimD
|
VLA-5 (very late activation antigen 5)
|
Glycoproteins
|
Monocytes
|
Binding
|
|||
Pertactin
|
unknown carbohydrate ligand
|
Saccharides
|
Eukaryotic cells
|
Binding
|
|||
Pertussis toxin
|
Haptoglobin
|
Glycoproteins
|
Binding
|
||||
PT (subunit S2 of B oligomer)
|
Haptoglobin
|
Glycoproteins
|
Binding
|
||||
Adhesins
|
terminal Gal(3SO4) β1- residues
|
Sulfoglycosphingolipids
|
Gal(3SO4)(b
|
Binding
|
|||
Adhesins
|
Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)
|
Oligoglycosylceramides
|
Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
|||
"P-selectin mimic, MSP2"
|
Fucosylated PSGL-1 (P-selectin glycoprotein ligand-1)
|
Glycoproteins
|
Binding
|
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01