GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▼	Target Source	Glycan Sequence	Binding	PubMed ID
Vibrio cholerae	Unknown	DSPG (Disialosyl paragloboside)	Disialoglycosphingolipids		NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Escherichia coli	Heat-labile enterotoxin	DSPG (Disialosyl paragloboside)	Disialoglycosphingolipids		NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Escherichia coli	Unknown	DSPG (Disialosyl paragloboside)	Disialoglycosphingolipids		NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Vibrio cholerae	Cholera toxin	DSPG (Disialosyl paragloboside)	Disialoglycosphingolipids		NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Escherichia coli	F1C	DSPG (Disialosyl paragloboside)	Disialoglycosphingolipids		NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	10816509
Clostridium tetani	Unknown	DSPG (Disialosyl paragloboside)	Disialoglycosphingolipids		NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Clostridium tetani	Tetanus toxin	DSPG (Disialosyl paragloboside)	Disialoglycosphingolipids		NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Escherichia coli	PapG	alpha-D-galactopyranosyl-(1-4)-beta-D-galactopyranose	Disaccharides	Uroepithelial cells	Gal(a1-4)Gal	Binding	2886993
Escherichia coli	K1	unnamed ligand	Disaccharides	Endothelial cells	GlcNAc(b1-4)GlcNAc	Binding	16564136
Clostridium botulinum	Progenitor toxin (type A)	Lactose	Disaccharides	Intestine-407 cells	Gal(b1-4)Glc	Binding	15850798