GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule ▼	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Legionella pneumophila	Adhesins	GD1a	Disialoglycosphingolipids	Human epithelial cells (respiratory tract)	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	14687561
Legionella pneumophila	Adhesins	GM3(NeuAc)	Monosialoglycosphingolipids	Human epithelial cells (respiratory tract)	NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	14687561
Legionella pneumophila	Adhesins	GM1	Monosialoglycosphingolipids	Human epithelial cells (respiratory tract)	Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	14687561
Legionella pneumophila	Adhesins	GM2(NeuAc)	Monosialoglycosphingolipids	Human epithelial cells (respiratory tract)	GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	14687561
Neisseria gonorrhoeae	Adhesins	unnamed ligand	Oligosaccharides	Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva	Gal(b1-4)GlcNAc(b1-4)Gal(b1-4)Glc	Binding	2115881
Streptococcus suis	Adhesins	Gb2 (Galabiosylceramide)	Diosylceramides		Gal(a1-4)Gal(b1-1)Cer	Binding	7961660
Streptococcus pneumoniae	Adhesins	unnamed ligand	Disaccharides		GalNAc(b1-4)Gal	Binding	6886624
Neisseria gonorrhoeae	Adhesins	Lactotriaosylceramide (Lc3)	Oligoglycosylceramides		GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	2115881
Streptococcus gordonii	Adhesins	Sialic acid	Monosaccharides	HL-60 promyelocytic leukemia cell line, Leukosialin (CD43)		Binding	11035744
Helicobacter pylori	Adhesins	Gangliosides	Sialoglycosphingolipids	Human leukocytes, Human neutrophils		Binding	10569742