PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▼ | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Unknown
|
116 kDa glycoprotein (containing sialic acid residues with N-linked glycans)
|
N-glycans
|
Neurones of all brain regions
|
Binding
|
|||
Capsid VP1
|
GD1a-GT1b analog
|
Sialoglycosphingolipids
|
(broad range)
|
Binding
|
|||
Type 4-pili
|
Surface-localized glycoconjugates (non-sialylated GSL and glycoproteins)
|
Glycoconjugates
|
Human epithelial cells
|
Binding
|
|||
Adhesins
|
Fibrinogen
|
Glycoproteins
|
Human type II alveolar cells (A549)
|
Binding
|
|||
Type 4-pili
|
Agglutinin glycoproteins containing O-/N-linked (poly)lactosamine and hybrid oligosaccharides
|
Glycoproteins
|
Human saliva
|
Binding
|
|||
Adhesins
|
hCG (human chorionic gonadotropin)
|
Glycoproteins
|
Erythrocytes
|
Binding
|
|||
FimD
|
VLA-5 (very late activation antigen 5)
|
Glycoproteins
|
Monocytes
|
Binding
|
|||
VP1 protein (RGD motif)
|
αvβ3 Integrin
|
Glycoproteins
|
BHK-21/LLC-MK2/HeLa/BK-LF
|
Binding
|
|||
Unknown
|
MUC16 mucin
|
Glycoproteins
|
Human corneal-limbal epithelial(HCLE) cells
|
Binding
|
|||
Unknown
|
Junctional adhesion molecule A (JAM-A)
|
Glycoproteins
|
Most organs including the central nervous system/heart/liver
|
Binding
|
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01