Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Database | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
|
Glycoprotein (GP)
|
O-mannosyl glycans on alpha-dystroglycan (DG)
|
O-glycans
|
Fibroblasts, Epithelial cells, Endothelial cells, Hepatocytes
|
Binding
|
|||
|
Glycoprotein (GP)
|
O-mannosyl glycans on alpha-dystroglycan (DG)
|
O-glycans
|
Fibroblasts, Epithelial cells, Endothelial cells, Hepatocytes
|
Binding
|
|||
|
Unknown
|
unnamed ligand
|
Sialoglycosphingolipids
|
Frog brain
|
NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
|
Unknown
|
unnamed ligand
|
Sialoglycosphingolipids
|
Frog brain
|
NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
|
Unknown
|
unnamed ligand
|
Sialoglycosphingolipids
|
Frog brain
|
Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
|
Unknown
|
unnamed ligand
|
Sialoglycosphingolipids
|
Frog brain
|
Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Shiga-like toxin (Stx1)
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
GI/kidney
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Unknown
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
GI/kidney
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
SabA (sialic acid-binding adhesin)
|
Sialyl Lewis x (SLex) antigen
|
Oligosaccharides
|
Gastric epithelial progenitors (GEPs)
|
NeuAc(a2-3)Gal(b1-4)
|
Binding
|
||
|
HpaA
|
Sialyl Lewis x (SLex) antigen
|
Oligosaccharides
|
Gastric epithelial progenitors (GEPs)
|
NeuAc(a2-3)Gal(b1-4)
|
Binding
|
Displaying entries 171 - 180 of 1840 in total
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International Collaboration
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Acknowledgements
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
