GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule ▲	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Coxsackievirus	Unknown	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides		Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	2168971
Clostridium tetani	Unknown	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides		Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Pseudomonas cepacia	Unknown	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides		Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	12628483
Rotavirus	Unknown	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides		Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	8574698
Pseudomonas maltophilia	Unknown	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides		Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	3413084
Borrelia burgdorferi	Unknown	Chondroitin 4-sulfate (C-4S)	Glycosaminoglycans	Vero cells		Not Binding	9826395
Paramyxovirus	Unknown	116 kDa glycoprotein (containing sialic acid residues with N-linked glycans)	N-glycans	Neurones of all brain regions		Binding	11666031
Staphylococcus aureus	Unknown	MUC16 mucin	Glycoproteins	Human corneal-limbal epithelial(HCLE) cells		Binding	17898272
Reovirus	Unknown	Junctional adhesion molecule A (JAM-A)	Glycoproteins	Most organs including the central nervous system/heart/liver		Binding	18216114
Borrelia burgdorferi	Unknown	Heparin (N-desulfated, N-acetylated)	Glycosaminoglycans	Vero cells		Binding	9826395