GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule ▲	Ligand Name	Ligand Feature	Target Source	Binding	PubMed ID
Borrelia burgdorferi	Unknown	Heparin (completely desulfated, N-acetylated)	Glycosaminoglycans	Vero cells	Not Binding	9826395
Actinomyces odontolyticus	Unknown	unknown carbohydrate ligand	Saccharides	Tongue	Binding	9712794
Influenza virus	Unknown	Endothelial cell-specific molecule (ESM)	Proteoglycans		Not Binding	1740131
Foot-and-mouth disease virus	VP1 (RGD peptide)	αvβ3 Integrin (independent of expression of Heparan sulfate on cell-sulface)	Glycoproteins	Extracellular matrix (ECM)	Binding	9557639
Foot-and-mouth disease virus	VP1 (RGD peptide)	Heparin	Glycosaminoglycans	Extracellular matrix (ECM)	Binding	9557639
Foot-and-mouth disease virus	VP1 (RGD peptide)	Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface)	Glycosaminoglycans	Extracellular matrix (ECM)	Binding	9557639
Foot-and-mouth disease virus	VP1 (RGD peptide)	Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface)	Glycosaminoglycans	Extracellular matrix (ECM)	Binding	9557639
Foot-and-mouth disease virus	VP1 (RGD peptide)	Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface)	Glycosaminoglycans	Extracellular matrix (ECM)	Binding	9557639
Foot-and-mouth disease virus	VP1 (RGD peptide)	Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface)	Glycosaminoglycans	Extracellular matrix (ECM)	Binding	9557639
Foot-and-mouth disease virus	VP1 (RGD peptide)	Heparin	Glycosaminoglycans	Extracellular matrix (ECM)	Not Binding	9557639