PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule ▲ | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
VP1 protein (RGD motif)
|
αvβ3 Integrin
|
Glycoproteins
|
BHK-21/LLC-MK2/HeLa/BK-LF
|
Binding
|
|||
VP2 amino acids on puff B
|
Sialic acid (α2,3)
|
Saccharides
|
Central nervous system
|
NeuAc(a2-3)
|
Binding
|
||
VP8
|
Sialic acid
|
Monosaccharides
|
Epithelial cells of small intestine
|
Binding
|
|||
VP8
|
Sialic acid
|
Monosaccharides
|
Binding
|
||||
VP8 (galectin)
|
Sialic acid(2-O-methyl-α-Neu5Ac (Neu5Ac2Me))
|
Monosaccharides
|
Binding
|
||||
VP8 (spike protein)
|
Sialic acid(2-O-methyl-α-Neu5Gc (Neu5Gc2Me))
|
Monosaccharides
|
Binding
|
||||
VP8 (spike protein)
|
Sialic acid
|
Monosaccharides
|
Binding
|
||||
Verotoxin
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
|||
Verotoxin
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
|||
Verotoxin (1)
|
unnamed ligand
|
Oligosaccharides
|
Gal(a1-4)Gal(b1-4)Glc(b
|
Binding
|
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01