Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Species Pathogen Adherence Molecule ▲ Ligand Name Ligand Feature Target Source Glycan Sequence Binding PubMed ID
Verotoxin (1/2c)
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
Oligoglycosylceramides
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
Verotoxin (1; B-subunit)
CD77 (Globotriaosylceramide; Gb3)
Oligoglycosylceramides
Germinal center B lymphocytes, Burkitt's lymphoma cells
Gal(a1-4)Gal
Binding
Verotoxin (2)
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
Oligoglycosylceramides
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
Viral protein
NeuAc/GlcNAc/(GlcNAc)n side chains of WGA-binding glycoproteins
Glycoproteins
Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13)
NeuAc/GlcNAc/(GlcNAc)n
Binding
Viral protein
NeuAcα2,3-Gal/GalNAc side chains of MAA-binding glycoproteins
Glycoproteins
Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13)
NeuAc(a2-3)Gal/GalNAc
Binding
Viral protein
α-mannose and α-glucose side chains of ConA-binding glycoproteins
Glycoproteins
Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13)
Man/Glc
Binding
Virus Spike Protein VP4 (mapped between aminoacids 93 and 208 of its trypsin cleavage fragment VP8)
Sialic acid-containing cell compounds
Glycoconjugates
Binding
Yeast cells and conidia
Fibronectin
Glycoproteins
Extracellular matrix (ECM)
Binding
Yeast cells and hyphae
Fibronectin
Glycoproteins
Extracellular matrix (ECM)
Binding
Yeast cells and hyphae
Laminin
Glycoproteins
Extracellular matrix (ECM)
Binding
Displaying entries 1821 - 1830 of 1840 in total

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01