GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species ▲	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Glycan Sequence	Binding	PubMed ID
Yersinia pestis	PsaA/B (pH-6 antigen)	GQ1b	Tetrasialoglycosphingolipids	NeuAc(a2-8)NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	9712817
Yersinia pestis	PsaA/B (pH-6 antigen)	GT1b	Trisialoglycosphingolipids	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	9712817
Yersinia pestis	PsaA/B (pH-6 antigen)	Galactosylceramide (nonhydroxylated fatty acids)	Monoglycosylceramides	Gal(b1-1)Cer	Not Binding	9712817
Yersinia pestis	PsaA/B (pH-6 antigen)	Glucosylceramide	Monoglycosylceramides	Glc(b1-1)Cer	Not Binding	9712817
Yersinia pestis	PsaA/B (pH-6 antigen)	Galactosylceramide (hydroxylated fatty acids)	Monoglycosylceramides	Gal(b1-1)Cer	Binding	9712817
Yersinia pestis	PsaA/B (pH-6 antigen)	Gb4 (Globoside; Globotetraose; P antigen)	Oligoglycosylceramides	GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	9712817
Yersinia pestis	PsaA/B (pH-6 antigen)	Gb5 (Forssman glycolipid)	Oligoglycosylceramides	GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	9712817
Yersinia pestis	PsaA/B (pH-6 antigen)	Lactosylceramide (Lactocerebroside)	Diosylceramides	Gal(b1-4)Glc(b1-1)Cer	Binding	9712817
Yersinia pestis	PsaA/B (pH-6 antigen)	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides	Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	9712817
Yersinia pestis	PsaA/B (pH-6 antigen)	Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)	Oligoglycosylceramides	Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	9712817