GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID ▼
Human immunodeficiency virus	Unknown	Galactosylceramide (or derivative)	Monoglycosylceramides	Human colon epithelial HT29 cells	Gal(b1-1)Cer	Binding	1378511
Rhinovirus	Unknown	ICAM-1 (intercellular adhesion molecule-1) domain1/2	Glycoproteins	Primary chicken embryo fibroblasts (CEFs)		Binding	1356290
Coronavirus	Unknown	MHVR (murine member of the carcinoembryonic antigen family of glycoproteins)	Glycoproteins	BHK-21 cells		Binding	1318394
Streptococcus pneumoniae	Unknown	unnamed ligand	Oligosaccharides	Chinchilla tubotympanum	Gal(b1-4)GlcNAc(b1-3)Gal(b	Binding	1298868
Escherichia coli	PrsG (class III) G adhesins	Gb5 (Forssman glycolipid)	Oligoglycosylceramides	Acute cystitis patients	GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding
Escherichia coli	P-fimbriae	Gb5 (Forssman glycolipid)	Oligoglycosylceramides	Acute cystitis patients	GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding
Escherichia coli	PapG (class II) G adhesins	Gal alpha 1-4 Gal-containing isoreceptors	Glycosphingolipids	Patient with septic infection or pyelonephritis	Gal(a1-4)Gal	Binding
Escherichia coli	P-fimbriae	Gal alpha 1-4 Gal-containing isoreceptors	Glycosphingolipids	Patient with septic infection or pyelonephritis	Gal(a1-4)Gal	Binding
Escherichia coli	P-fimbriae	Gal alpha 1-4 Gal-containing isoreceptors	Glycosphingolipids	Pyelonephritis patients	Gal(a1-4)Gal	Binding
Escherichia coli	PapG (class I) G adhesins	Gal alpha 1-4 Gal-containing isoreceptors	Glycosphingolipids	Pyelonephritis patients	Gal(a1-4)Gal	Binding