GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence ▲	Binding	PubMed ID
Escherichia coli	PapG (class II) G adhesins	Gal alpha 1-4 Gal-containing isoreceptors	Glycosphingolipids	Patient with septic infection or pyelonephritis	Gal(a1-4)Gal	Binding
Escherichia coli	P-fimbriae	Gal alpha 1-4 Gal-containing isoreceptors	Glycosphingolipids	Patient with septic infection or pyelonephritis	Gal(a1-4)Gal	Binding
Escherichia coli	P-fimbriae	Gal alpha 1-4 Gal-containing isoreceptors	Glycosphingolipids	Pyelonephritis patients	Gal(a1-4)Gal	Binding
Escherichia coli	P-pili	Globo-series GSL	Glycosphingolipids	Uroepithelial cells, Erythrocytes	Gal(a1-4)Gal	Binding	9973330
Escherichia coli	PapG	Globo-series GSL	Glycosphingolipids	Uroepithelial cells, Erythrocytes	Gal(a1-4)Gal	Binding	9973330
Escherichia coli	PapG (class I) G adhesins	Gal alpha 1-4 Gal-containing isoreceptors	Glycosphingolipids	Pyelonephritis patients	Gal(a1-4)Gal	Binding
Escherichia coli	P-fimbriae	unnamed ligand	Oligosaccharides		Gal(a1-4)Gal(b	Binding	2885220
Burkholderia cepacia	Lectin-like proteins (adhesin)	Gb2 (Galabiosylceramide)	Diosylceramides	Sputa of cystic fibrosis patients	Gal(a1-4)Gal(b1-1)Cer	Binding	8606110
Escherichia coli	P-fimbriae	Gb2 (Galabiosylceramide)	Diosylceramides	Urine	Gal(a1-4)Gal(b1-1)Cer	Binding	16564136
Escherichia coli	P-pili	Gb2 (Galabiosylceramide)	Diosylceramides	Epithelial cells in human urinary tract	Gal(a1-4)Gal(b1-1)Cer	Binding	9007266