PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Hemagglutinin H1(1934)
|
Human and avian receptors containing sialylated glycoconjugates
|
Glycoconjugates
|
Airways
|
Binding
|
|||
PA-IIL
|
Lewis a (Lea) (GSL)
|
Glycosphingolipids
|
Airways
|
Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Unknown
|
Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)
|
Oligoglycosylceramides
|
Apical membrane of cystic fibrosis epithelia
|
Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Unknown
|
Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)
|
Oligoglycosylceramides
|
Apical membrane of cystic fibrosis epithelia, Patients with pneumonia
|
Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Residues 226 (glutamine) and 228 (glycine)
|
Sialic acid linked to α2,3Galβ1,3GalNAc
|
Oligosaccharides
|
Avian/equine isolates
|
NeuAc(a2-3)Gal(b1-3)GalNAc
|
Binding
|
||
Unknown
|
MHVR (murine member of the carcinoembryonic antigen family of glycoproteins)
|
Glycoproteins
|
BHK-21 cells
|
Binding
|
|||
VP1 protein (RGD motif)
|
αvβ3 Integrin
|
Glycoproteins
|
BHK-21/LLC-MK2/HeLa/BK-LF
|
Binding
|
|||
Type 1-pili
|
D-Mannose
|
Monosaccharides
|
Bladder epithelium
|
Man
|
Binding
|
||
FimCH-chaperone-adhesin complex
|
D-Mannose
|
Monosaccharides
|
Bladder epithelium
|
Man
|
Binding
|
||
Type 4-pili
|
Thyroglobulin containing N-linked complex and hybrid (oligomannosidic) glycans
|
Glycoproteins
|
Bovine
|
Binding
|
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01