GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▲	Target Source	Glycan Sequence	Binding	PubMed ID
Rotavirus	Unknown	Lactosylceramide (t18:0-h16:0-h24:0)	Diosylceramides		Gal(b1-4)Glc(b1-1)Cer	Binding	11160731
Burkholderia cepacia	Lectin-like proteins (adhesin)	Gb2 (Galabiosylceramide)	Diosylceramides	Sputa of cystic fibrosis patients	Gal(a1-4)Gal(b1-1)Cer	Binding	8606110
Escherichia coli	P-fimbriae	Gb2 (Galabiosylceramide)	Diosylceramides	Urine	Gal(a1-4)Gal(b1-1)Cer	Binding	16564136
Escherichia coli	P-pili	Gb2 (Galabiosylceramide)	Diosylceramides	Epithelial cells in human urinary tract	Gal(a1-4)Gal(b1-1)Cer	Binding	9007266
Helicobacter pylori	35S-labeled or 125I-labeled proteins	Lactosylceramide (d18:1-16:0/24:1)	Diosylceramides	Human granulocytes, Human erythrocytes	Gal(b1-4)Glc(b1-1)Cer	Not Binding	9499377
Helicobacter pylori	35S-labeled or 125I-labeled proteins	Lactosylceramide (d18:1-h16:0/t18:0-h24:0/t18:0-h16:0)	Diosylceramides	Dog small intestine	Gal(b1-4)Glc(b1-1)Cer	Binding	9499377
Escherichia coli	F1C	Lactosylceramide (d18:1-16:0/24:1)	Diosylceramides	Human neutrophils	Gal(b1-4)Glc(b1-1)Cer	Not Binding	11877427
Escherichia coli	F1C	Gb2 (Galabiosylceramide)	Diosylceramides	Synthetic	Gal(a1-4)Gal(b1-1)Cer	Not Binding	11877427
Neisseria gonorrhoeae	Lectin-like proteins (adhesin)	Gb2 (Galabiosylceramide)	Diosylceramides	Gonorrhoeae patients	Gal(a1-4)Gal(b1-1)Cer	Not Binding	2468365
Escherichia coli	PapG (class II)	Gb2 (Galabiosylceramide)	Diosylceramides	Epithelial cells in human urinary tract	Gal(a1-4)Gal(b1-1)Cer	Binding	9007266