Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Species Pathogen Adherence Molecule ▲ Ligand Name Ligand Feature Target Source Glycan Sequence Binding PubMed ID
"OspA, OspB, OspC"
Lactosylceramide (Lactocerebroside)
Diosylceramides
Gal(b1-4)Glc(b1-1)Cer
Binding
"P-selectin mimic, MSP2"
Fucosylated PSGL-1 (P-selectin glycoprotein ligand-1)
Glycoproteins
Binding
(class I)
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
Oligoglycosylceramides
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
(class I/II)
Gb4 (Globoside; Globotetraose; P antigen)
Oligoglycosylceramides
GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
(class I/II)
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
Oligoglycosylceramides
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
(class I/II)
GL-IV glycolipid
Glycolipids
Binding
(class I/II)
GL-III glycolipid
Glycolipids
Binding
(class I/II/III)
Gb5 (Forssman glycolipid)
Oligoglycosylceramides
GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
(class I/II/III)
Globo-A
Oligoglycosylceramides
Binding
(class I/III)
GL-IV glycolipid
Glycolipids
Not Binding
Displaying entries 11 - 20 of 1840 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01