GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID ▼
Streptococcus pneumoniae	FcsSBP (fucose solute-binding protein)	Blood group A antigen	Oligosaccharides		GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc	Binding	19285508
Pseudomonas aeruginosa	LecB	alpha-methyl-fucoside	Monosaccharides	A549 cells		Binding	19237519
Pseudomonas aeruginosa	LecA	Alpha-methyl-galactoside	Monosaccharides	A549 cells		Binding	19237519
Escherichia coli	K88	Neoglycans (PSA-Lac)	Glycoproteins	Porcine serum albumin(PSA)		Binding	19101589
Norovirus	Unknown	Sialylated type 2 chain conjugates (S-type 2-HSA)	Glycoproteins	Human serum albumin	NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD	Binding	19054801
Norovirus	Unknown	Sialyl Lewis x (SLex-HSA)	Glycoproteins	Human serum albumin	NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD	Binding	19054801
Norovirus	Unknown	Blood group B antigen (B-tri-HSA)	Glycoproteins	Human serum albumin	Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Binding	19054801
Norovirus	Unknown	Blood group A antigen (A-tri-HSA)	Glycoproteins	Human serum albumin	GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Binding	19054801
Norovirus	Unknown	Sialyl-dimeric Lewis x (SdiLex-HSA)	Glycoproteins	Human serum albumin	NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD	Binding	19054801
Norovirus	Unknown	Blood group H1 antigen (HSA)	Glycoproteins	Human serum albumin	Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD	Binding	19054801