GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▲	Glycan Sequence	Binding	PubMed ID
Escherichia coli	Heat-labile enterotoxin	GD2	Disialoglycosphingolipids	GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	7527546
Clostridium tetani	Tetanus toxin	GD1a	Disialoglycosphingolipids	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Clostridium tetani	Tetanus toxin	GD3(NeuAc)	Disialoglycosphingolipids	NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Clostridium tetani	Tetanus toxin	GD2	Disialoglycosphingolipids	GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Influenza virus	Unknown	GD3(Neu5Ac9Ac)	Disialoglycosphingolipids	Ac(-9)NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7870741
Influenza virus	Unknown	GD1b	Disialoglycosphingolipids	Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	7870741
Influenza virus	Unknown	GD2	Disialoglycosphingolipids	GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	7870741
Vibrio cholerae	Unknown	GD1a	Disialoglycosphingolipids	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Vibrio cholerae	Unknown	GD3(NeuAc)	Disialoglycosphingolipids	NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Vibrio cholerae	Unknown	GD2	Disialoglycosphingolipids	GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546