GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▼	Target Source	Glycan Sequence	Binding	PubMed ID
Neisseria gonorrhoeae	Unknown	Dextran sulfate	Polysaccharides	Human epithelial cells		Binding	9420059
Plasmodium falciparum	Unknown	Polylactosamine of band 3	Polysaccharides			Binding	8574698
Foot-and-mouth disease virus	Natural ligand of integrin [alpha]v[beta]3	Dextran sulfate	Polysaccharides	Extracellular matrix (ECM)		Not Binding	8764038
Actinomyces naeslundii	Unknown	unnamed ligand	Polyglycosylceramides	Rat small intestine	GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	2358461
Actinomyces viscosus	Unknown	unnamed ligand	Polyglycosylceramides	Rat small intestine	GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461
Shigella dysenteriae	B subunit	unnamed ligand	Polyglycosylceramides	Rat small intestine	GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5	Not Binding	3543013
Shigella dysenteriae	Shiga toxin	unnamed ligand	Polyglycosylceramides		GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5	Not Binding	2435422
Escherichia coli	Unknown	unnamed ligand	Polyglycosylceramides		GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5	Binding	2435422
Shigella dysenteriae	Unknown	unnamed ligand	Polyglycosylceramides		GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5	Not Binding	2435422
Escherichia coli	S-fimbriae	unnamed ligand	Oligosaccharides	Neural cell lines	NeuAc(a2-3)Gal(b1-3)GalNAc	Binding	16564136