Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Species Pathogen Adherence Molecule Ligand Name Ligand Feature Target Source Glycan Sequence ▼ Binding PubMed ID
P-fimbriae
DSGG (Disialosyl galactosyl globoside, disialyl Gb5)
Disialoglycosphingolipids
Human kidney tissues
NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
PapG (class II)
DSGG (Disialosyl galactosyl globoside, disialyl Gb5)
Disialoglycosphingolipids
Human kidney tissues
NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
B subunit
DSGG (Disialosyl galactosyl globoside, disialyl Gb5)
Disialoglycosphingolipids
Human erythrocytes
NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Not Binding
Unknown
unnamed ligand
Oligosaccharides
Murine small plaque
NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc
Binding
Unknown
Sialylated oligosaccharides
Oligosaccharides
Erythrocytes
NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc
Binding
Capsid protein VP1
Sialylated oligosaccharides
Oligosaccharides
Cell surface
NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc
Binding
Neutrophil-activating proteins (150-kDa)
Sialyl Lewis a (SLea) (GSL)
Monosialoglycosphingolipids
Human bile bladder tumor
NeuAc(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
Not Binding
Unknown
Sialyl Lewis a (SLea) (GSL)
Monosialoglycosphingolipids
NeuAc(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
Binding
Unknown
Sialyl Lewis a (SLea) (GSL)
Monosialoglycosphingolipids
NeuAc(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
Not Binding
Unknown
NeuAc3-Lc4Cer (Sialyl lactotetraosylceramide)
Sialoglycosphingolipids
NeuAc(a2-3)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
Binding
Displaying entries 191 - 200 of 1840 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01