GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source ▼	Glycan Sequence	Binding	PubMed ID
Escherichia coli	PapG (class II) G adhesins	Gal alpha 1-4 Gal-containing isoreceptors	Glycosphingolipids	Patient with septic infection or pyelonephritis	Gal(a1-4)Gal	Binding
Escherichia coli	P-fimbriae	Gal alpha 1-4 Gal-containing isoreceptors	Glycosphingolipids	Patient with septic infection or pyelonephritis	Gal(a1-4)Gal	Binding
Vibrio cholerae	MSHA (mannose/glucose-specific hemagglutinin)	Mannose	Monosaccharides	Patient with acute watery diarrhea	Man	Binding	10219594
Vibrio cholerae	MSHA (mannose/glucose-specific hemagglutinin)	Glucose	Monosaccharides	Patient with acute watery diarrhea	Glc	Binding	10219594
Norovirus	Unknown	Terminal N-Acetylgalactosamine residue in an alpha linkage	Saccharides	Oyster digestive tissues		Binding	16707048
Moraxella catarrhalis	Fimbriae	Asialo-GM2 (Gangliotriosylceramide; GgO3)	Oligoglycosylceramides	Other than pharyngeal epithelial cells	GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	12137200
Parvovirus	Unknown	Sialic acid (both O- and N-linked)	Monosaccharides	Nucleated bovine cells		Binding	15269359
Paramyxovirus	Unknown	116 kDa glycoprotein (containing sialic acid residues with N-linked glycans)	N-glycans	Neurones of all brain regions		Binding	11666031
Human immunodeficiency virus	Envelope glycoprotein gp120	Galactosyl sulfatide	Sulfoglycosphingolipids	Neural receptor	HSO3(-3)Gal(b1-1)Cer	Binding	1871126
Human immunodeficiency virus	Envelope glycoprotein gp120	Galactosylceramide (Galactocerebroside)	Monoglycosylceramides	Neural receptor	Gal(b1-1)Cer	Binding	1871126