Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Database | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule ▲ | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
|
Botulinum neurotoxin (16S)
|
N-Acetylgalactosamine
|
Monosaccharides
|
Intestinal epithelial cells (T84)
|
GalNAc
|
Binding
|
||
|
Botulinum neurotoxin (16S)
|
Galactose
|
Monosaccharides
|
Intestinal epithelial cells (T84)
|
Gal
|
Binding
|
||
|
Botulinum neurotoxin (16S)
|
N-Acetylglucosamine
|
Monosaccharides
|
Intestinal epithelial cells (T84)
|
GlcNAc
|
Not Binding
|
||
|
Botulinum neurotoxin (16S)
|
Mannose
|
Monosaccharides
|
Intestinal epithelial cells (T84)
|
Man
|
Not Binding
|
||
|
Botulinum neurotoxin (16S)
|
Glucose
|
Monosaccharides
|
Intestinal epithelial cells (T84)
|
Glc
|
Not Binding
|
||
|
Botulinum neurotoxin (16S)
|
Fucose
|
Monosaccharides
|
Intestinal epithelial cells (T84)
|
Fuc
|
Not Binding
|
||
|
Botulinum neurotoxin (type C)
|
GD1b
|
Disialoglycosphingolipids
|
Presynaptic neuronal cells
|
Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Botulinum neurotoxin (type C)
|
GT1b
|
Trisialoglycosphingolipids
|
Presynaptic neuronal cells
|
NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Botulinum neurotoxin (type D)
|
Phosphatidylethanolamine (PE)
|
Non-glycosylated Lipids
|
Presynaptic neuronal cells
|
Binding
|
|||
|
C-terminal domain of toxin A molecules
|
unnamed ligand
|
Oligosaccharides
|
Human colonic cells
|
Gal(a1-3)Gal(b1-4)GlcNAc
|
Binding
|
Displaying entries 201 - 210 of 1840 in total
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International Collaboration
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Acknowledgements
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
