GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID ▼
Human immunodeficiency virus	gp120	Sulfatide (CSE)	Sulfoglycosphingolipids	Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells	HSO3(-3)Gal(b1-1)Cer	Binding	15973004
Human immunodeficiency virus	gp120	Galactosylceramide (Galactocerebroside)	Monoglycosylceramides	Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells	Gal(b1-1)Cer	Binding	15973004
Pseudomonas aeruginosa	Unknown	Asialo-GM2 (Gangliotriosylceramide; GgO3)	Oligoglycosylceramides	Cystic fibrosis patients	GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	15973004
Mycoplasma pneumoniae	Unknown	Glycoproteins with terminal NeuAcα3Galβ4GlcNAc-sequences	Glycoproteins		NeuAc(a2-3)Gal(b1-4)GlcNAc	Binding	15973004
Vibrio cholerae	Cholera toxin	GM1	Monosialoglycosphingolipids		Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	15973004
Clostridium tetani	Tetanus neurotoxin	GM2(NeuAc)	Monosialoglycosphingolipids		GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	15973004
Clostridium botulinum	Neurotoxin (type A/B)	GM2(NeuAc)	Monosialoglycosphingolipids		GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	15973004
Clostridium perfringens	Delta toxin	GM2(NeuAc)	Monosialoglycosphingolipids		GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	15973004
Vibrio cholerae	Unknown	GM1	Monosialoglycosphingolipids		Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	15973004
Clostridium perfringens	Unknown	GM2(NeuAc)	Monosialoglycosphingolipids		GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	15973004