GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▼	Target Source	Glycan Sequence	Binding	PubMed ID
Polyoma virus	Capsid protein VP1	Sialylated oligosaccharides	Oligosaccharides	Cell surface	NeuAc(a2-3)Gal(b1-3)GalNAc	Binding	8805524
Helicobacter pylori	Unknown	unnamed ligand	Oligosaccharides	Stomach	NeuAc(a2-3)Gal(b1-4)GlcNAc	Binding	16564136
Polyoma virus	Unknown	Sialylated oligosaccharides	Oligosaccharides	Erythrocytes	NeuAc(a2-3)Gal(b1-3)GalNAc	Binding	6316632
Escherichia coli	K99	unnamed ligand	Oligosaccharides	Intestinal cells	NeuAc(a2-3)Gal(b1-4)Glc	Binding	16564136
Influenza virus	Residues 226 (glutamine) and 228 (glycine)	Sialic acid linked to α2,3Galβ1,3GalNAc	Oligosaccharides	Avian/equine isolates	NeuAc(a2-3)Gal(b1-3)GalNAc	Binding	7975212
Polyoma virus	Unknown	unnamed ligand	Oligosaccharides	Murine small plaque	NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc	Binding	8574698
Actinomyces naeslundii	Type-2 fimbrial lectins (130-kDa glycoprotein)	unnamed ligand	Oligosaccharides	Polymorphonuclear leukocytes (PMNs)	Gal(b1-3)GalNAc	Binding	7790078
Streptococcus suis	PO	unnamed ligand	Oligosaccharides	human erythrocytes	Gal(a1-4)Gal	Binding	7499414
Escherichia coli	Type 1-fimbriae	trisaccharide: Man(a1-3)Man(b1-4)GlcNAc	Oligosaccharides	Patient with urinary tract infection	Man(a1-3)Man(b1-4)GlcNAc	Binding	6138149
Clostridium difficile	Toxin A	unnamed ligand	Oligosaccharides	Human colonic cells	Gal(a1-3)Gal(b1-4)GlcNAc	Binding	12507507