GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species ▼	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Staphylococcus aureus	SSL11	Sialyl Lewis x (SLex) antigen	Oligosaccharides	(broad range)	NeuAc(a2-3)Gal(b1-4)	Binding	18809496
Staphylococcus aureus	Unknown	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides	Apical membrane of cystic fibrosis epithelia, Patients with pneumonia	Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	7708767
Staphylococcus aureus	Unknown	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides		Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	3413084
Staphylococcus aureus	Unknown	MUC16 mucin	Glycoproteins	Human corneal-limbal epithelial(HCLE) cells		Binding	17898272
Sporothrix schenckii	Yeast cells and conidia	Fibronectin	Glycoproteins	Extracellular matrix (ECM)		Binding	11598061
Sporothrix schenckii	Yeast cells and hyphae	Fibronectin	Glycoproteins	Extracellular matrix (ECM)		Binding	15351036
Sporothrix schenckii	Yeast cells and hyphae	Laminin	Glycoproteins	Extracellular matrix (ECM)		Binding	15351036
Sporothrix schenckii	Unknown	Lactosylceramide (Lactocerebroside)	Diosylceramides	Human lung, Human polymorphonuclear leukocytes	Gal(b1-4)Glc(b1-1)Cer	Binding	2194958
Shigella flexneri	Type 1-fimbriae	Mannose	Monosaccharides		Man	Binding	2885220
Shigella dysenteriae	B subunit	Gb4 (Globoside; Globotetraose; P antigen)	Oligoglycosylceramides	Human erythrocytes	GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	3543013