GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source ▲	Glycan Sequence	Binding	PubMed ID
Helicobacter pylori	35S-labeled or 125I-labeled proteins	Asialo-GM2 (Gangliotriosylceramide; GgO3)	Oligoglycosylceramides	Guinea pig erythrocytes	GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	9499377
Lactobacillus johnsonii	Unknown	Asialo-GM2 (Gangliotriosylceramide; GgO3)	Oligoglycosylceramides	Guinea pig erythrocytes	GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	11087711
Helicobacter pylori	35S-labeled or 125I-labeled proteins	GgO3 (de-N- acylated)	Oligoglycosylceramides	Guinea pig erythrocytes	GalNH2(b1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	9499377
Escherichia coli	F1C	Asialo-GM2 (Gangliotriosylceramide; GgO3)	Oligoglycosylceramides	Guinea pig erythrocytes	GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	11877427
Influenza virus	Unknown	Glycoproteins	Glycoproteins	Guinea pig serum		Not Binding	1740131
Escherichia coli	18-kDa fimbrial adhesin	Galactose derivatives	Saccharides	HEp-2 cells	Gal	Binding	11368522
Campylobacter upsaliensis	5 bacterial surface proteins (50 to 90-kDa)	Phosphatidylethanolamine (PE)	Non-glycosylated Lipids	HEp-2 cells		Binding	8926069
Campylobacter upsaliensis	Unknown	Lyso-PE	Non-glycosylated Lipids	HEp-2 cells		Binding	8926069
Shigella dysenteriae	Adhesins	Lipid extracts of Hep-2 cells	Non-glycosylated Lipids	HEp-2 cells		Binding	11381327
Actinomyces naeslundii	Adhesins	Asialofetuin	Glycoproteins	HL-60 promyelocytic leukemia cell line		Binding	11035744