PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
35S-labeled or 125I-labeled proteins
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Human erythrocytes, Rabbit intestine
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
PapG (class II)
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Human erythrocytes
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Lectin-like proteins (adhesin)
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Gonorrhoeae patients
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
Unknown
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Vero cells
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Unknown
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
GI/kidney
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Stx
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Ubiquitously expressed in most tissues (e.g. human erythrocytes/endothelium/kidney/platelet)
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Unknown
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Human erythrocytes
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
Unknown
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Human colon adenocarcinoma cells (WiDr )
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
Unknown
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Human erythrocytes
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
B subunit
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
HeLa cells, Rabbit jejunul mucosa
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01