Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Species Pathogen Adherence Molecule Ligand Name Ligand Feature Target Source Glycan Sequence ▲ Binding PubMed ID
35S-labeled or 125I-labeled proteins
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
Oligoglycosylceramides
Human erythrocytes, Rabbit intestine
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Not Binding
PapG (class II)
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
Oligoglycosylceramides
Human erythrocytes
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
Lectin-like proteins (adhesin)
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
Oligoglycosylceramides
Gonorrhoeae patients
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Not Binding
Unknown
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
Oligoglycosylceramides
Vero cells
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
Unknown
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
Oligoglycosylceramides
GI/kidney
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
Stx
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
Oligoglycosylceramides
Ubiquitously expressed in most tissues (e.g. human erythrocytes/endothelium/kidney/platelet)
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
Unknown
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
Oligoglycosylceramides
Human erythrocytes
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Not Binding
Unknown
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
Oligoglycosylceramides
Human colon adenocarcinoma cells (WiDr )
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Not Binding
Unknown
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
Oligoglycosylceramides
Human erythrocytes
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Not Binding
B subunit
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
Oligoglycosylceramides
HeLa cells, Rabbit jejunul mucosa
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
Displaying entries 221 - 230 of 1840 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01