GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species ▼	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Shigella dysenteriae	Adhesins	GM1	Monosialoglycosphingolipids		Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	11381327
Shigella dysenteriae	Shiga toxin	Gb4 (Globoside; Globotetraose; P antigen)	Oligoglycosylceramides		GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	2435422
Shigella dysenteriae	Unknown	Gb4 (Globoside; Globotetraose; P antigen)	Oligoglycosylceramides		GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	2435422
Shigella dysenteriae	Adhesins	Colonic mucin	Glycoproteins	Colon		Binding	11381327
Shigella dysenteriae	Stx	Platelet-specific GSL (Stx band 0.03)	Glycosphingolipids	Human platelets		Binding	9712788
Shigella dysenteriae	B subunit	Gb2 (Galabiosylceramide)	Diosylceramides	Human meconium	Gal(a1-4)Gal(b1-1)Cer	Binding	3543013
Shigella dysenteriae	B subunit	unnamed ligand	Glycosphingolipids	Human meconium	Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	3543013
Shigella dysenteriae	B subunit	Gal-nLc4Cer; P1 antigen (GSL)	Oligoglycosylceramides	Human type B erythrocytes	Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	3519828
Shigella dysenteriae	B subunit	isoGb3 (Isoglobotriaosylceramide; iGb3)	Oligoglycosylceramides	Dog small intestine	Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	3543013
Shigella dysenteriae	B subunit	unnamed ligand	Oligoglycosylceramides	Human kidney	GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	3543013