GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule ▲	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Escherichia coli	CS3 (coli surface 3)-fimbriae	GM2(NeuAc)	Monosialoglycosphingolipids	Intestinal epithelium, Rabbit intestine	GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	7822033
Escherichia coli	CS3 (coli surface 3)-fimbriae	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides	Intestinal epithelium, Rabbit intestine	Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	7822033
Streptococcus pneumoniae	CTB-PsaA pentamers	GM1	Monosialoglycosphingolipids	Serum, Saliva, Nasal/bronchial wash samples	Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	15358234
Streptococcus gordonii	Ca2+-independent lectins	Hs antigen	Glycoproteins		NeuAc(a2-3)Gal(b1-4)Glc-HSA	Binding	9393794
Streptococcus gordonii	Ca2+-independent lectins	Fetuin	Glycoproteins			Binding	9393794
Streptococcus gordonii	Ca2+-independent lectins	Hs antigen	Glycoproteins		GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc-HSA	Binding	9393794
Polyoma virus	Capsid VP1	GD1a-GT1b analog	Sialoglycosphingolipids	(broad range)		Binding	18809496
Polyoma virus	Capsid protein VP1	Sialylated oligosaccharides	Oligosaccharides	Cell surface	NeuAc(a2-3)Gal(b1-3)GalNAc	Binding	8805524
Polyoma virus	Capsid protein VP1	Sialylated oligosaccharides	Oligosaccharides	Cell surface	NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc	Binding	8805524
Norovirus	Capsid proteins	Blood group B antigen	Oligosaccharides		Gal(a1-3)[Fuc(a1-2)]Gal	Binding	18809496