GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▲	Glycan Sequence	Binding	PubMed ID
Vibrio cholerae	Unknown	DSPG (Disialosyl paragloboside)	Disialoglycosphingolipids	NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Escherichia coli	Heat-labile enterotoxin	DSPG (Disialosyl paragloboside)	Disialoglycosphingolipids	NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Escherichia coli	Unknown	DSPG (Disialosyl paragloboside)	Disialoglycosphingolipids	NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Vibrio cholerae	Cholera toxin	DSPG (Disialosyl paragloboside)	Disialoglycosphingolipids	NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Escherichia coli	F1C	DSPG (Disialosyl paragloboside)	Disialoglycosphingolipids	NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	10816509
Clostridium tetani	Unknown	DSPG (Disialosyl paragloboside)	Disialoglycosphingolipids	NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Clostridium tetani	Tetanus toxin	DSPG (Disialosyl paragloboside)	Disialoglycosphingolipids	NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	7527546
Escherichia coli	S-fimbriae	alpha-sialyl-beta-2,3-galactose-containing glycolipids and glycoproteins	Glycoconjugates	NeuAc(a2-3)Gal(b	Binding	2883653
Escherichia coli	S-fimbriae	unnamed ligand	Glycoconjugates	NeuAc(a2-3)Gal(b	Binding	11454740
Escherichia coli	SfaS	unnamed ligand	Glycoconjugates	NeuAc(a2-3)Gal(b	Binding	10341176