GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species ▲	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Candida albicans	"Extracellular polymeric material, acid proteinase, chitin"	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides	Human buccal epihelial cells (BECs)	Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	8005674
Chlamydia pneumoniae	Unknown	Asialo-GM2 (Gangliotriosylceramide; GgO3)	Oligoglycosylceramides		GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	12628483
Chlamydia pneumoniae	Unknown	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides		Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	12628483
Chlamydia trachomatis	Unknown	Asialo-GM2 (Gangliotriosylceramide; GgO3)	Oligoglycosylceramides		GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	12628483
Chlamydia trachomatis	Unknown	N-acetyl-b-maltoheptaosylamine sulfate (SM)	Oligosaccharides	HeLa cells		Binding	9420059
Chlamydia trachomatis	Unknown	Pentosan polysulfate (PP)	Polysaccharides	HeLa cells		Binding	9420059
Chlamydia trachomatis	Unknown	Dextran sulfate	Polysaccharides	HeLa cells		Binding	9420059
Chlamydia trachomatis	Unknown	NAC-heparin (non-anticoagulant heparin)	Glycosaminoglycans	HeLa cells		Binding	9420059
Chlamydia trachomatis	Unknown	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides		Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	12628483
Clostridium botulinum	Botulinum neurotoxin (type C)	GD1b	Disialoglycosphingolipids	Presynaptic neuronal cells	Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	18242046