GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID ▼
Staphylococcus aureus	Unknown	GalNAcβ4Gal-containing GSLs	Glycosphingolipids		GalNAc(b1-4)Gal	Binding	15973004
Influenza virus	Unknown	Neuraminic acid-containing sialoglycosphingolipids	Sialoglycosphingolipids			Binding	15973004
Human immunodeficiency virus	Unknown	Cluster of differentiation 4 (CD4)	Glycoproteins			Binding	15973004
Escherichia coli	S-fimbriae	NeuAcα3Galβ-containing glycoproteins	Glycoproteins	Lumenal surfaces of the vascular endothelium in the neonatal rat brain	NeuAc(a2-3)Gal(b	Binding	15973004
Escherichia coli	SfaS	NeuAcα3Galβ-containing glycoproteins	Glycoproteins	Lumenal surfaces of the vascular endothelium in the neonatal rat brain	NeuAc(a2-3)Gal(b	Binding	15973004
Pseudomonas aeruginosa	Unknown	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides	Cystic fibrosis patients	Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	15973004
Helicobacter pylori	SabA (sialic acid-binding adhesin)	Sialyl-dimeric Lewis x (SdiLex) (GSL)	Monosialoglycosphingolipids		NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	15973004
Escherichia coli	SfaA	Lactosylceramide (Lactocerebroside)	Diosylceramides		Gal(b1-4)Glc(b1-1)Cer	Binding	15973004
Escherichia coli	S-fimbriae	Lactosylceramide (Lactocerebroside)	Diosylceramides		Gal(b1-4)Glc(b1-1)Cer	Binding	15973004
Escherichia coli	P-fimbriae	Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)	Oligoglycosylceramides		Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	15973004