GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▲	Target Source	Glycan Sequence	Binding	PubMed ID
Influenza virus	Unknown	Sia2-3Gal-containing receptors	Glycoconjugates		NeuAc(a2-3)Gal	Binding	9882316
Influenza virus	Hemagglutinin	Human and avian receptors containing sialylated glycoconjugates	Glycoconjugates	Airways		Binding	18809496
Histoplasma capsulatum	Lectin-like component	Galactosylated surface molecules (mainly β-anomer)	Glycoconjugates	Murine macrophages		Binding	19547878
Influenza virus	Hemagglutinin H1(1934)	Human and avian receptors containing sialylated glycoconjugates	Glycoconjugates	Airways		Binding	18809496
Paramyxovirus	Hemagglutinin H1(1934)	Human and avian receptors containing sialylated glycoconjugates	Glycoconjugates	Airways		Binding	18809496
Escherichia coli	Type 1-fimbriae	β-D-glycosides	Glycoconjugates	Patient with urinary tract infection		Binding	6138149
Plasmodium falciparum	Unknown	Neuraminidase-insensitive, trypsin sensitive carbohydrate ligand	Glycoconjugates	Molecules on the erythrocyte membrane (other than glycophorins A and B)		Binding	3308959
Listeria monocytogenes	Unknown	α-GalCer/CD1d tetramers	Glycoconjugates	V[alpha]14+ NK1.1- T cells in infected liver of mice		Binding	16988270
Influenza virus	SNA lectins	Minor NeuAcα6-containing molecules	Glycoconjugates	Human leukocytes		Binding	11030743
Escherichia coli	Type 1-fimbriae	Glycoside p-nitrophenyl alpha-D-mannopyranoside	Glycoconjugates	Patient with urinary tract infection		Binding	6138149