GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name ▼	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Norovirus	Unknown	Terminal N-Acetylgalactosamine residue in an alpha linkage	Saccharides	Oyster digestive tissues		Binding	16707048
Escherichia coli	FimH	Tamm-Horsfall protein (THP)	Glycoproteins			Binding	12010488
Escherichia coli	Type 1-pili	Tamm-Horsfall protein (THP)	Glycoproteins			Binding	12010488
Escherichia coli	Type 1-fimbriae	Synthetic branched oligosaccharides: Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)]Man(a1-3)Man	Oligosaccharides	Patient with urinary tract infection	Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)Man(a1-3)]Man	Binding	6138149
Escherichia coli	Type 1-fimbriae	Synthetic branched oligosaccharides: Man(a1-3)[Man(a1-6)]Man(a1-6)Man(a1-3)Man	Oligosaccharides	Patient with urinary tract infection	Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-3)]Man	Binding	6138149
Escherichia coli	P-pili	Surfactant-like particles (SLP)	Non-glycosylated Lipids	Human colonocytes and enterocytes		Binding	10531281
Escherichia coli	PapD-PapG (class I)	Surfactant-like particles (SLP)	Non-glycosylated Lipids	Human colonocytes and enterocytes		Binding	10531281
Pseudomonas aeruginosa	Type 4-pili	Surface-localized glycoconjugates (non-sialylated GSL and glycoproteins)	Glycoconjugates	Human epithelial cells		Binding	9224879
Mycoplasma pneumoniae	Unknown	Sulfo-lactosylceramide (SM3)	Sulfoglycosphingolipids	Human colon adenocarcinoma cells (WiDr )	HSO3(-3)Gal(b1-4)Glc(b1-1)Cer	Binding	2470753
Cytomegalovirus	Unknown	Sulfo-lactosylceramide (SM3)	Sulfoglycosphingolipids		HSO3(-3)Gal(b1-4)Glc(b1-1)Cer	Binding	9780061