PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
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Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Virus Spike Protein VP4 (mapped between aminoacids 93 and 208 of its trypsin cleavage fragment VP8)
|
Sialic acid-containing cell compounds
|
Glycoconjugates
|
Binding
|
||||
Neurotoxin (type B)
|
Complex of synaptotagmin II and ganglioside GT1b or GD1a
|
Glycoconjugates
|
Binding
|
||||
Unknown
|
Complex of synaptotagmin II and ganglioside GT1b or GD1a
|
Glycoconjugates
|
Binding
|
||||
Type 4-pili
|
Surface-localized glycoconjugates (non-sialylated GSL and glycoproteins)
|
Glycoconjugates
|
Human epithelial cells
|
Binding
|
|||
S-fimbriae (SfaA)
|
Seminolipid (Sulfogalactosylglycerolipid)
|
Glycolipids
|
Brain endothelial cells
|
Gal(3SO4)(b1-1)-alkylacylglycerol
|
Binding
|
||
P-fimbriae
|
Gal alpha 1-4 Gal-containing glicolipids
|
Glycolipids
|
Pyelonephritis patients
|
Gal(a1-4)Gal
|
Binding
|
||
PapG
|
Gal alpha 1-4 Gal-containing glicolipids
|
Glycolipids
|
Pyelonephritis patients
|
Gal(a1-4)Gal
|
Binding
|
||
FHA (filamentous hemagglutinin)
|
Galactose on sulfated glycolipids
|
Glycolipids
|
Gal
|
Binding
|
|||
PrsG
|
Gal alpha 1-4 Gal-containing glicolipids
|
Glycolipids
|
Gal(a1-4)Gal
|
Binding
|
|||
PapG
|
Gal alpha 1-4 Gal-containing glicolipids
|
Glycolipids
|
Gal(a1-4)Gal
|
Binding
|
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01