GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▲	Target Source	Glycan Sequence	Binding	PubMed ID
Rotavirus	Virus Spike Protein VP4 (mapped between aminoacids 93 and 208 of its trypsin cleavage fragment VP8)	Sialic acid-containing cell compounds	Glycoconjugates			Binding	9261399
Clostridium botulinum	Neurotoxin (type B)	Complex of synaptotagmin II and ganglioside GT1b or GD1a	Glycoconjugates			Binding	9712688
Clostridium botulinum	Unknown	Complex of synaptotagmin II and ganglioside GT1b or GD1a	Glycoconjugates			Binding	9712688
Pseudomonas aeruginosa	Type 4-pili	Surface-localized glycoconjugates (non-sialylated GSL and glycoproteins)	Glycoconjugates	Human epithelial cells		Binding	9224879
Escherichia coli	S-fimbriae (SfaA)	Seminolipid (Sulfogalactosylglycerolipid)	Glycolipids	Brain endothelial cells	Gal(3SO4)(b1-1)-alkylacylglycerol	Binding	8098039
Escherichia coli	P-fimbriae	Gal alpha 1-4 Gal-containing glicolipids	Glycolipids	Pyelonephritis patients	Gal(a1-4)Gal	Binding	8574698
Escherichia coli	PapG	Gal alpha 1-4 Gal-containing glicolipids	Glycolipids	Pyelonephritis patients	Gal(a1-4)Gal	Binding	8574698
Bordetella pertussis	FHA (filamentous hemagglutinin)	Galactose on sulfated glycolipids	Glycolipids		Gal	Binding	12640357
Escherichia coli	PrsG	Gal alpha 1-4 Gal-containing glicolipids	Glycolipids		Gal(a1-4)Gal	Binding	12640357
Escherichia coli	PapG	Gal alpha 1-4 Gal-containing glicolipids	Glycolipids		Gal(a1-4)Gal	Binding	12640357