Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Database | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▼ |
|---|---|---|---|---|---|---|---|
|
Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa).
|
N-Acetylgalactosamine
|
Monosaccharides
|
Intestinal cells
|
GalNAc
|
Binding
|
||
|
Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa).
|
Galactose
|
Monosaccharides
|
Intestinal cells
|
Gal
|
Binding
|
||
|
Raft-like plasma membrane domains
|
N-Acetylgalactosamine
|
Monosaccharides
|
Intestinal cells
|
GalNAc
|
Binding
|
||
|
Raft-like plasma membrane domains
|
Galactose
|
Monosaccharides
|
Intestinal cells
|
Gal
|
Binding
|
||
|
Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa).
|
β-2 and β-7 integrins
|
Glycoproteins
|
Intestinal cells
|
Binding
|
|||
|
Raft-like plasma membrane domains
|
β-2 and β-7 integrins
|
Glycoproteins
|
Intestinal cells
|
Binding
|
|||
|
Viral protein
|
NeuAc/GlcNAc/(GlcNAc)n side chains of WGA-binding glycoproteins
|
Glycoproteins
|
Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13)
|
NeuAc/GlcNAc/(GlcNAc)n
|
Binding
|
||
|
Viral protein
|
NeuAcα2,3-Gal/GalNAc side chains of MAA-binding glycoproteins
|
Glycoproteins
|
Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13)
|
NeuAc(a2-3)Gal/GalNAc
|
Binding
|
||
|
Viral protein
|
α-mannose and α-glucose side chains of ConA-binding glycoproteins
|
Glycoproteins
|
Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13)
|
Man/Glc
|
Binding
|
||
|
Shiga toxin (Stx2)
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Vero cells
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
Displaying entries 261 - 270 of 1840 in total
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International Collaboration
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Acknowledgements
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
