Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Database | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species ▲ | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
|
HA
|
Fucose
|
Monosaccharides
|
Intestinal epithelial cells (T84)
|
Fuc
|
Not Binding
|
||
|
Neurotoxin (type A/B)
|
GD2
|
Disialoglycosphingolipids
|
GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
|||
|
Unknown
|
GD2
|
Disialoglycosphingolipids
|
GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
|||
|
Botulinum neurotoxin
|
GT1b (complex with synaptotagmin II)
|
Trisialoglycosphingolipids
|
Presynaptic membrane of neuromuscular junction
|
Binding
|
|||
|
BoNT/B
|
GT1b (complex with synaptotagmin II)
|
Trisialoglycosphingolipids
|
Presynaptic membrane of neuromuscular junction
|
Binding
|
|||
|
Neurotoxin (type B)
|
Complex of synaptotagmin II and ganglioside GT1b or GD1a
|
Glycoconjugates
|
Binding
|
||||
|
Unknown
|
Complex of synaptotagmin II and ganglioside GT1b or GD1a
|
Glycoconjugates
|
Binding
|
||||
|
Toxin A
|
α-Gal on Fab of IgA(κ) MAb
|
Glycoproteins
|
Mouse
|
Gal
|
Binding
|
||
|
Toxin A
|
α-Gal on Fab of IgM(λ) MAb
|
Glycoproteins
|
Mouse
|
Gal
|
Binding
|
||
|
Unknown
|
α-Gal on Fab of IgA(κ) MAb
|
Glycoproteins
|
Mouse
|
Gal
|
Binding
|
Displaying entries 271 - 280 of 1840 in total
To see the latest features, please visit our beta site.
International Collaboration
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Acknowledgements
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
