GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence ▲	Binding	PubMed ID
Propionibacterium granulosum	Unknown	Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)	Oligoglycosylceramides		Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2435422
Escherichia coli	Unknown	Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)	Oligoglycosylceramides		Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	3298243
Streptococcus suis	Unknown	Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)	Oligoglycosylceramides		Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	8440715
Streptococcus suis	Unknown	Neoglycoproteins (containing P1 Antigen)	Glycoproteins		Gal(a1-4)Gal(b1-4)GlcNAc	Binding	8440715
Shigella dysenteriae	B subunit	Gal-nLc4Cer; P1 antigen (GSL)	Oligoglycosylceramides	Human type B erythrocytes	Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	3519828
Shigella dysenteriae	B subunit	Gal-nLc4Cer; P1 antigen (GSL)	Oligoglycosylceramides	Human erythrocytes	Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	3543013
Shigella dysenteriae	Shiga toxin	Gal-nLc4Cer; P1 antigen (GSL)	Oligoglycosylceramides		Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	2435422
Escherichia coli	Unknown	Gal-nLc4Cer; P1 antigen (GSL)	Oligoglycosylceramides		Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	2435422
Shigella dysenteriae	Unknown	Gal-nLc4Cer; P1 antigen (GSL)	Oligoglycosylceramides		Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	2435422
Pseudomonas aeruginosa	PA-IL (51-kDa)	Melibiose	Disaccharides		Gal(a1-6)Glc	Binding	15049333